Mitochondria are the body's "energy factories," and their proper function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system acts like ...
Mitochondria are known as the body’s “energy factories,” and their function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system ...
The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.
Figure 1 BET inhibition is synthetic lethal to OXPHOS blockage in liver cancer. Left: GDH1-dependent glutamine metabolic remodeling upon BET inhibition. Right: “Synthetic lethality” targeting OXPHOS ...