All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

Most knowledge on centrioles has been built by studying dividing animal cells in a narrow group of species, like flies or humans. “Recent technological advances in several fronts allow us to study ...

Centrioles, the barrel-shaped organelles best known for their role in cell division, may also put their stamp on early embryos. In a newly fertilized embryo, the centrioles that are present come ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...

Centrosomes are not essential for cell division in most animal cells, although they contribute to the efficiency of mitotic spindle assembly. Centrosome loss is tolerated surprisingly well in fly ...

As the primary microtubule-organizing center (MTOC) of the cell, the centrosome is a major structural determinant of the mitotic spindle. Like each chromosome, the centrosome must replicate once and ...

Scientists at Johns Hopkins say they have learned that most cells will not divide without centrioles, and they found out why. The p53 protein, already known to prevent cell division for other reasons, ...

Centrioles are cylindrical structures involved in the generation of microtubules - fibers inside of cells that form a network to provide structure and shape to cells and to mediate transport processes ...

Fella Tamzalit, Diana Tran, Weiyang Jin, Vitaly Boyko, Hisham Bazzi, Ariella Kepecs, Lance C. Kam, Kathryn V. Anderson, Morgan Huse Proceedings of the National ...

Researchers have identified a new structure in human sperm that functions in the zygote and may provide new avenues for addressing male infertility and insights into early embryo developmental defects ...

The new information, plus new tools for centriole manipulation, should help researchers figure out how p53 helps safeguard cells, and how it causes cancers when it doesn't. "P53 was already known to ...