Nature

Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator

SRp38 is an atypical SR protein that functions as a general splicing repressor when dephosphorylated. We now show that phosphorylated SRp38 functions as a sequence-specific splicing activator. Unlike ...
JSTOR Daily

Distinct Nuclear and Cytoplasmic Functions of Androgen Receptor Cofactor p44 and Association with Androgen-Independent Prostate Cancer

Yi Peng, Fei Chen, Jonathan Melamed, Luis Chiriboga, Jianjun Wei, Xiangtian Kong, Maureen Mcleod, Yirong Li, Caihong X. Li, Alice Feng, Michael J. Garabedian, Zhengxin Wang, Robert G. Roeder, Peng Lee ...
Nature

Accessory molecules for Toll-like receptors and their function

Toll-like receptors (TLRs) are type I transmembrane proteins that are involved in innate and adaptive immune responses to pathogens and are found on the surface of cells and in endosomal compartments.
JSTOR Daily

Small Heat Shock Protein Hspl7.8 Functions as an AKR2A Cofactor in the Targeting of Chloroplast Outer Membrane Proteins in Arabidopsis

Plastid proteins that are encoded by the nuclear genome and synthesized in the cytosol undergo posttranslational targeting to plastids. Ankyrin repeat protein 2A (AKR2A) and AKR2B were recently shown ...