Naltrexone has long been used to treat alcohol use disorder. Now it’s gaining attention as a tool for people who want to cut ...

Struggling with alcohol cravings? Naltrexone targets the brain's reward center to minimize drinking urges and reduce harmful ...

WASHINGTON (AP) — U.S. regulators have greenlighted a new weight-loss drug called Contrave, the third in a string of approvals for prescription medications aimed at the nation’s 78 million obese ...

SAN DIEGO, Dec. 11, 2013 -- Orexigen® Therapeutics, Inc. (Nasdaq: OREX) today announced that the Company has resubmitted the Contrave® New Drug Application to the United States (U.S.) Food and Drug ...

On Tuesday, the LaJolla, Calif.-based developer of a drug it calls Contrave tries to succeed where at least three other pharmaceutical firms have failed in recent years -- to win over a panel of ...

Although it's been used since the 1980s, naltrexone remains a relatively unknown treatment for alcohol dependency. Costing around £3 per pill, the drug blocks the "euphoric and sedative effects" of ...

I spoke to six people who struggled with drinking too much until they got a prescription for naltrexone from Oar Health. Read ...

Contrave is a combination therapy consisting of naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant. Results showed no statistically significant difference in the incidence ...

Data to be shared during an ObesityWeek press conference include four of seven presentations supporting CONTRAVE and its utility in helping people lose weight BRENTWOOD, Tenn., Nov. 4, 2025 ...

Orexigen announced that it has resubmitted a New Drug Application (NDA) to the FDA for Contrave (naltrexone sustained release [SR]/bupropion SR), an investigational drug for weight loss and ...

Orexigen Therapeutics Inc. said Tuesday that U.S. health officials declined to approve the experimental weight loss pill Contrave and want the company to conduct an additional study to address ...