Unlike nuclear DNA, mitochondrial DNA (mtDNA) is circular in nature and organized as mitochondrial nucleoids comprised of DNA-protein complexes that are distributed in the matrix. It is also inherited ...

An elusive step in the process of human DNA replication has been observed, for the first time, by scientists. The step, which is crucial for DNA replication in humans and other forms of life, had ...

Scientists have captured new details of the biochemical interactions necessary for cell division. The research may suggest ways for stopping cell division when it goes awry. Building on earlier work ...

Two teams of researchers have uncovered microscopic details of how a protein called photolyase uses light to repair DNA. The discovery could help develop sustainable technologies for chemical ...

DSBs arise from genotoxic insults and normal physiological processes such as DNA replication 1. The ATM protein, a member of the PI3K-like kinase family, is mutated in patients with ataxia ...

For the first time, an elusive step in the process of human DNA replication has been demystified by scientists at Penn State University. According to senior author Stephen J. Benkovic, an Evan Pugh ...