Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

The SWI/SNF Ig-Fold for Transcription Factor Interactions or 'SWIFT' domain on mSWI/SNF chromatin remodeling complexes engage ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

A patient death in a CRISPR trial halts gene editing studies, raising critical safety questions. What this means for the ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave. Researchers have now mapped this hidden architecture in unprecedented detail, showing ...

“Expression tells us what cells do, but regulatory DNA tells us where they come from, how they develop, and which germ layer ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

BUFFALO, N.Y. – The University at Buffalo team that discovered how a gene found in 75% of us protects against neurodegeneration has now found that this same gene enhances immune function as well. The ...