An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20 th in the ...

Researchers from the University of Michigan Rogel Cancer Center have found a mechanism for why a subset of patients’ tumors grow, rather than shrink, when faced with immunotherapy. Immunotherapy has ...

The JAK2 gene is a protein-coding gene of the Janus kinase family. It plays a role in cellular signaling. Evidence notes connections between this gene and some medical conditions. Variations in this ...

Researchers at Weill Cornell Medicine report that a rare gene mutation that delays Alzheimer’s disease does so by damping inflammatory signaling in brain-resident immune cells in a preclinical study.

Insulin resistance plays a role in many diseases. The new research provides insights into why insulin resistance appears to be associated with neurodegenerative disorders. Corresponding author Kai ...

Biomarkers, molecules found in blood or other biological tissues that signal a condition, disease, or process, are very valuable in helping doctors recommend the most effective treatment for a patient ...

Linking nanoparticles to antibodies that stick to a heat-sensitive channel in the body called TRPV1, researchers can open the channel by warming the nanoparticles with radiowaves, allowing calcium to ...

ZURICH, May 13 (Reuters) - Gene Signal is in talks with potential partners to help develop its new treatment for a leading cause of blindness in the elderly, the biotech firm's chief executive said on ...

Uncovering the mechanisms behind plant defense signaling can improve strategies to protect crops against disease.