Intermediate filaments (IFs) are critical parts of the structure of cells. They are essential for both normal tissue structure and function. Enabling cells to withstand the stretch and pressure on the ...

Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

Animal cell shape is largely determined by the cortex, a thin actin network underlying the plasma membrane in which myosin-driven stresses generate contractile tension. Tension gradients result in ...