Are inhibitors of the JAK/STAT Signaling Pathway a potential treatment for Parkinson Disease? How does -syn lead to activation of the JAK/STAT pathway, and how does this contribute to ...
Figure 1: STAT is a target of miR-279. Figure 3: STAT is a critical target of miR-279 in vivo. Figure 5: A model of the gene regulatory circuit required to specify non-migratory anterior follicle cell ...
Originally characterized as a growth factor for erythrocytes, erythropoietin (EPO) is used to treat anemia and fatigue in cancer patients receiving radiation therapy and chemotherapy. EPO and the EPO ...
The Janus kinase/signal transducer and activator of transcription (Jak/Stat) pathway was discovered 20 years ago as a mediator of cytokine signaling. Since this time, more than 2,500 articles have ...
The JAK/STAT (Janus Kinase-Signal Transducer and Activator of Transcription) signalling pathway controls the activity of various cytokines and growth factors. The ...
Positron emission tomography (PET) and estrogen receptor (ER) ligand in patients with invasive breast cancer. Germline single nucleotide polymorphisms (SNPs) in XRCC3, XRCC1, and XPD, and survival ...
Jonathan Silverberg, MD, PhD, MPH, associate professor of dermatology, director of clinical research and patch testing, George Washington University School of Medicine and Health Sciences, discusses ...
A conserved signaling axis linking Drosophila adipose tissue to nephrocyte function reveals how obesity can drive kidney dysfunction and points to new opportunities for therapeutic intervention.
Recludix Pharma, a clinical-stage company leading the discovery and development of inhibitors of challenging targets for ...
A global team of researchers at the Max Planck Institute of Biochemistry has made a groundbreaking discovery that saves the lives of patients suffering from toxic epidermal necrolysis. This rare but ...
Leveraging advanced spatial proteomics, scientists have identified the JAK/STAT pathway as a critical target for treating toxic epidermal necrolysis, offering new hope for patients with this ...
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