MALDI-TOF (matrix-assisted laser desorption/ionization time-of-flight) mass spectroscopy is a form of molecular analysis that can be used in forensic investigation to identify remains and estimate the ...

Using MALDI-TOF, researchers can quickly and accurately determine polymer, protein and nucleic acid masses. They can also analyze and resolve complex assortments of smaller peptides and ...

A continuous region of coding sequence can be PCR amplified using a 5′ primer possessing a polymerase binding site and a translation initiation site in-frame with the 5′ end of the test sequence. The ...

Recently developed Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectrometry (MALDI-TOF-MS) requires innovative methods for designing automated liquid handling systems. An overview ...

What is time-of-flight mass spectrometry? How ToF MS has gained more interest since the commercialization of MALDI. Why a high-speed ADC is key to ToF MS performance. Mixed-signal front end that ...

Perhaps no tool has been as instrumental to the proteomics revolution as the mass spectrometer. With the ability to deconvolute highly complex mixtures over a wide range of abundance levels, these ...

The practice of laboratory clinical microbiology is finally changing driven by the assimilation of newer technologies, like Matrix Assisted Laser Desorption Ionization - Time of Flight/Mass ...

In order to design and develop new pharmaceutical compounds, the distribution of drugs and their metabolites in tissues must be determined to gain in-depth knowledge of the uptake of a drug into its ...

The School of Biosciences has been awarded £1.5M through the BBSRC ALERT 2024 program to acquire a cutting-edge rapid scanning ion mobility MALDI-TOF Mass Spectrometer. Mass spectrometry (MS) is an ...

Several considerations are necessary to prepare MALDI IMS samples, including section thickness, tissue washes, and matrix selection and application, which are generally optimized empirically for each ...

Dr. Markus Kostrzewa will elaborate on the progress that has been made in Bruker Microbiology & Diagnostics, specifically on the innovation and evolution of the FDA-cleared MALDI Biotyper ® CA System.