Tumor metastasis is a multi-step cascade process driven by molecular factors such as genetic mutations, epigenetic changes, and post-translational modifications. The tumor microenvironment (TME) plays ...

Not all cancer cells that successfully escape their native tissue and survive in circulation go on to seed metastases. Instead, variations in metastatic efficiency exist that determine whether a cell ...

A large-scale international study, led by researchers from the Gray Faculty of Medical and Health Sciences at Tel Aviv ...

Researchers found in mice that multiple nutrients and cancer cell characteristics work together to control the spread of ...

An international research team headed by scientists at the University of Cambridge has uncovered a mechanism that may underpin how aspirin could reduce the metastasis of some cancers by preventing an ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

The discovery could pave the way for new treatments, improved risk prediction, and earlier intervention for brain metastases.

A study led by researchers from the University of Arizona Cancer Center at UArizona Health Sciences identified a biological mechanism that could lead to more effective treatments for breast cancer ...

From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree ...

A new study published in Nature Communications heralded some fascinating findings on the future of drug development for neuroblastoma treatment. Cancer that forms in developing nerve cells, ...