This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it ...

The algorithm also identified a host of previously unknown mutations, including five that involve genes related to pigmentation. In these cases, iSAFE identified identical mutations in multiple ...

If you buy something using links in our stories, we may earn a commission. This helps support our journalism. Learn more. Please also consider subscribing to WIRED That concept was so powerful that we ...

Natural pathogenic bacteria populations can harbour mutator alleles (with high mutation rates) that may offer a selection advantage. In the March 30 Science, Giraud et al. describe a model to ...

In this paper, a mechanism called proximity inheritance is introduced in the birth–death process of a networked population involving the Prisoner's Dilemma game. Different from the traditional ...

Discover interesting facts about how evolution works, the different patterns that can emerge from evolution, how quickly organisms can evolve, and whether evolution is a random or ordered process When ...

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive ...

Selection isn’t in doubt, but many scientists have argued that most evolutionary changes appear at the level of the genome and are essentially random and neutral. Adaptive changes groomed by natural ...