The pathogenesis of Alzheimer’s Disease (AD), a leading cause of dementia, remains unclear. One notable limitation of current cellular models is that they lack an aging in vitro environment. Progerin ...
María Jesús Andrés, Carla Espinós (detrás), Rosa M Nevado (delante, al lado de MJA), Miguel de la Fuente, Rosa Carmona, Ana Barettino, Vicente Andrés, Pilar Gonzalo e Ignacio Benedicto.
Hutchinson-Gilford progeria syndrome (HGPS), an extremely rare genetic disorder, arises when a silent point mutation in the gene encoding the nuclear envelope protein lamin A, LMNA, leads to abnormal ...
Researchers found that the body’s natural recycling system, the lysosome, plays a vital role in removing the protein that drives premature aging. When this system breaks down, aging speeds up. By ...
Researchers at the University of Brighton have achieved a global first by creating genetically stable, lab-grown stem cell ...