RNA interference (RNAi) therapeutics have garnered significant attention in clinical research due to their potential for treating various diseases, including genetic disorders, viral infections and ...
The discovery of RNAi dates back to the 1990s when researchers observed unexpected gene silencing in plants and fungi. In 1998, Andrew Fire and Craig Mello published a groundbreaking study ...
Researchers have discovered RNA mechanisms that may lead to more effective, durable and targeted treatments for conditions like high cholesterol, liver diseases and cancers. RNA interference (RNAi) ...
Scientists have discovered a new CRISPR mechanism with precise activity, expanding the potential applications of the existing ...
La Jolla Labs was founded to make modern RNA biology and advanced computational techniques directly useful to patients whose ...
This review is designed by Dr. Junhong Han and written by his postdoctoral researcher Dr. Lei Qiu and PhD student Qian Jing (Research Laboratory of Tumor Epigenetics and Genomics, West China Hospital, ...
A novel CRISPR defense mechanism, unlike known nucleases, specifically destroys transfer ribonucleic acids (tRNA) that are ...
Cell fate commitment is achieved by the establishment of cell type-specific transcriptional programs, which in turn are guided, reinforced, and ultimately locked-in by epigenetic mechanisms. In a new ...
TORONTO--(BUSINESS WIRE)--Deep Genomics, a leading AI drug development company focused on decoding biology to program life-changing medicines, announced today the release of the manuscript, “An RNA ...