Figure 2: Electron density maps of the 30S, 50S and 70S ribosomal particles. Although high quality diffracting crystals of the ribosome have been available for a number of years 5,6, the technical ...
The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...
The Royal Swedish Academy of Sciences today awarded the 2009 Nobel Prize in Chemistry to scientists in the U.S., England, and Israel "for studies of the structure and function of the ribosome," the ...
In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...
Thomas A. Steitz, Sterling Professor of Molecular Biophysics and Biochemistry at Yale and one of three winners of the 2009 Nobel Prize in Chemistry, died Oct. 9 at his home in Stony Creek after a ...
Native 3D Structure of Eukaryotic 80S Ribosome: Morphological Homology with the E. coli 70S Ribosome
A three-dimensional reconstruction of the eukaryotic 80S monosome from a frozen-hydrated electron microscopic preparation reveals the native structure of this macromolecular complex. The new structure ...
The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...
This is a preview. Log in through your library . Abstract During protein synthesis, tRNAs and mRNA move through the ribosome between aminoacyl (A), peptidyl (P), and exit (E) sites of the ribosome in ...
A figure of the 80S ribosome structure. This image relates to an article that appeared in the Nov. 26, 2010, issue of Science, published by AAAS. The study, by Dr. Adam Ben-Shem at IGBMC (Institut de ...
Most people carry the fungus Candida albicans on their bodies, without this causing many problems. However, a systemic infection with this fungus is dangerous and difficult to treat. Few ...
Why is ribosome display used? Ribosome display can be used to study the protein-protein interactions that occur during everyday metabolism. In addition, the technique allows scientists to identify the ...
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