Cell invasion is a common characteristic of malignant cancers. This plays a central role in tumor metastasis and dissemination, and is largely responsible for deaths related to cancer (1, 2). Tumor ...

Drastic differences in the ways cells behave and respond to drugs are observed when cells are cultured using 3D instead of 2D approaches. These differences are driving the adoption of more advanced ...

An increasing amount of research indicates that more translational and appropriate observations can be made with organoids and micro-tissues in comparison with 2D monolayer cell models. This is most ...

Evaluating Anticancer Drugs and Building Tissue and Tumor Co-Culture Models Among Uses The need for new tools and technologies to decrease the cost of drug discovery and reduce animal testing has been ...

This article includes research findings that are yet to be peer-reviewed. Results are therefore regarded as preliminary and should be interpreted as such. Find out about the role of the peer review ...

Three dimensional (3D) cell culture has been an area of increasing interest and relevance across a wide breadth of fields for some time now. One type of 3D structure generated in vitro are spheroids.

In basic and applied biology research, such as investigations of stem cells and drug screening, spheroid cell cultures are valuable, providing a more realistic test environment than the 2D cultures ...

When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. Every coach of American-style football preaches it, but few players learn: If there is a fumble ...