Biological assailants like fungi, bacteria, and viruses continuously test natural defenses that have evolved over millennia. Newer and stranger particles that originate from burning fuels, harmful ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

The in vitro assays from CN-Bio are effective in predicting clinical outcomes. High-functioning, metabolically competent human single- and multi-organ models are used in studies on drug metabolism, ...

Despite an FDA green light for the use of animal testing alternatives in drug development, regulatory concerns may be keeping the industry from embracing them, data collected by the R&D organization ...

When developing drugs, we rely on animal models to test drugs in an entire system before first-in-human studies. However, animals aren’t human and interspecies differences in pharmacology, physiology, ...

Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-on-Chip" ...

For our Spotlight on patient-derived in vitro cell models, we surveyed our audience to find out the latest trends, opinions and behaviors in the field. This infographic summarizes the results from the ...

In this webinar, Bryan McQueen will discuss how a novel in vitro model of inflammatory bowel disease paves the way toward scientific discovery and developing cost-effective therapies. Ben Zeskind from ...

A small molecule known as 10H-phenothiazine reduced the loss of motor neurons, the nerve cells that are lost in SMA, in ...

For decades, preclinical testing in mice, rats, and nonhuman primates has been a crucial part of drug development, an important although not infallible way to ensure some measure of safety for human ...