The orexin (Orx) system plays a critical role in drug addiction and reward-related behaviors. The dynorphin (Dyn) system promotes depressive-like behavior and plays a key role in the aversive effects ...

A study coordinated by the UAB, based on computer models and human cell cultures, shows that big dynorphin, an endogenous opioid peptide, protects neurons against the cytotoxic effects of β-amyloid ...

Neuroscientists have identified a neural circuit in the amygdala, the brain's seat of emotion processing, that gives rise to anxiety. Their insight has revealed the critical role of a molecule called ...

Scientists have discovered a mechanism which stops the process of forgetting anxiety after a stress event. In experiments they showed that feelings of anxiety don’t subside if too little dynorphin is ...

Neuroscientists at Cold Spring Harbor Laboratory (CSHL) have identified a neural circuit in the amygdala, the brain’s seat of emotion processing, that gives rise to anxiety. Their insight has revealed ...