The structure of the RecBCD helicase, although not hexameric, shows how the action of the motor pulls the DNA across amino acid residues that serve as a wedge to separate the duplex 12. A similar ...

This movie shows the helicase protein complex from all angles, and reveals how its shape changes back and forth between two forms. The research team hypothesizes that the rocking action of this ...

Scientists who study biological systems at the molecular level have over the years looked to the structure of protein molecules-how the atoms are organized-to shed light on the diverse functions each ...

Comic book superheroes often combine their supernatural abilities in a coordinated effort to outwit and defeat the villain. Scientists with expertise in different techniques will often follow suit, ...

In a recent study published in the PNAS Journal, researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication. They characterized the ...

The RNA helicase DDX3X spends its days unwinding RNA:RNA duplexes and binding key mediators of RNA metabolism. A regulator of RNA transcription, splicing, nuclear export, and translation, DDX3X plays ...

New Haven, Conn. -- Research led by Anna Marie Pyle, professor of molecular biophysics and biochemistry at Yale University reveals how a protein from Hepatitis C (HCV) unwinds RNA, potentially ...

Scientists who study biological systems at the molecular level have over the years looked to the structure of protein molecules -- how the atoms are organized -- to shed light on the diverse functions ...