It takes just a few milliseconds: A vesicle, only a few nanometers in size and filled with neurotransmitters, approaches a cell membrane, fuses with it, and releases its chemical messengers into the ...

Most neurons receive thousands of synaptic inputs onto widely spread dendrites. Because of dendritic filtering, distant synapses should have less efficacy than proximal ones. To investigate this, we ...

Activity–dependent changes in synaptic strength, such as long–term potentiation (LTP), are believed to be critical for information processing in the mature brain and for the refinement of neuronal ...