The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

A genome-wide CRISPR study maps 331 genes essential for early brain development, identifying PEDS1 as a new ...

By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.

An international research team identified hundreds of genes essential for the development of brain cells, including one gene ...

What do cells want to be when they grow up, and how do they get there? Intrigued by these questions, many developmental biologists try to follow the journeys of cells from when they can virtually ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called 'blastoids,' and found ...