The FDA’s new draft guidance on Bayesian methodology signals a shift toward more flexible, data-driven clinical trial designs, enabling sponsors to use prior data and adaptive approaches to improve ...

FDA proposes framework clinical trial designs to guide Bayesian methods, improving efficiency in drug development for rare and pediatric conditions.

HealthDay News — The rate of early termination or withdrawal in head and neck squamous cell carcinoma (HNSCC) clinical trials (CTs) has increased since 2000, with strategic decisions and poor ...

Statistical fragility refers to the vulnerability of clinical trial results to minor changes in event outcomes. The fragility index quantifies this vulnerability by determining the minimum number of ...

Head and neck cancer trials are frequently derailed before they can deliver answers. A new analysis suggests that the most common reasons are sponsor decisions related to safety or effectiveness and ...

Post-Hoc Analysis Using Computer Automated Grading Indicated that Reproxalap is Statistically Superior to Vehicle (p=0.020) in Reducing Dry-Eye Associated Ocular Redness, the Primary Endpoint of Phase ...

AI tools will allow CalciMedica to analyze Phase 2 datasets to refine the target patient populations and efficacy endpoints for upcoming pivotal trials LA JOLLA, Calif., Oct. 14, 2025 /PRNewswire/ -- ...

DUBLIN--(BUSINESS WIRE)--The "Clinical Trials Market Forecast Report by Phase, Indication, Study Material, Country and Company 2025-2033" report has been added to ResearchAndMarkets.com's offering.