Kanazawa University, in collaboration with Osaka University and the National Institutes for Quantum Science and Technology, ...

Randomness inside cells can decide whether a cancer returns after chemotherapy or whether an infection survives antibiotics.

Why does cancer sometimes recur after chemotherapy? Why do some bacteria survive antibiotic treatment? In many cases, the ...

MIT scientists have achieved the first-ever lab synthesis of verticillin A, a complex fungal compound discovered in 1970. Its delicate structure stalled chemists for decades, despite differing from ...

How Estrogen Receptor Binds DNA. This illustration shows the estrogen receptor alpha (ERα, in orange) attaching to DNA (in blue) as a pair, or dimer. The image is based on real-time, high-speed atomic ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Here, we present a method to obtain free energy, rates, and ...

Study deciphers the molecular handshake between LDL receptors and apoB100, shedding light on cholesterol metabolism and its role in cardiovascular disease. Study: Structure of apolipoprotein B100 ...

Introduction: Melittin is a potent antimicrobial peptide from bee venom that is effective against both Gram-positive and Gram-negative bacteria. However, it is extremely toxic to mammalian cells and, ...

Department of Chemical Engineering and Bioengineering, University of New Hampshire, Durham, New Hampshire 03824, United States Department of Chemical Engineering and Bioengineering, University of New ...

cAMP response element-binding protein (CREB) is a ubiquitously expressed nuclear transcription factor, which can be constitutively activated regardless of external stimuli or be inducibly activated by ...

This elegant study presents important findings into how small molecules that were originally developed to inhibit the oncogenic kinase, BRAF, instead trigger activation of this kinase target.