Nvidia says that DLSS 4.5 delivers improved stability, enhanced anti-aliasing, reduced ghosting, and clearer images.
If your devices only support up to 4K at 60Hz, a "premium high-speed" HDMI cable (18Gbps, HDMI 2.0) is perfectly fine. Again, just avoid really old or thin cables. Early HDMI cables (HDMI 1.4 or older ...