Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Small nucleolar RNAs (snoRNAs) are a class of ...

Researchers at Yale School of Medicine said they’ve solved a longstanding mystery of how mutations in the C9ORF72 gene, a common genetic cause of amyotrophic lateral sclerosis (ALS), may lead to toxic ...

Aided by two molecular control factors, the spliceosome rejects pre-mRNA that could be incorrectly spliced. While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome, which ...

Accurate gene expression requires that the enzyme that polymerizes RNA stops at the proper site (termination). In addition, multiple RNA processing reactions, including removal of intervening ...

We may receive a commission on purchases made from links. Ask an electrical engineer, automotive repair tech, appliance repair person, or even an electronics hobbyist what is most likely to cause an ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor ...

Construction of an O-GlcNAc responsive GFP biosensor. a. Schematic of the GFP reporter (left, drawn to scale) and predicted changes in reporter splicing and expression upon varying cellular O-GlcNAc ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, USA Department of Orthodontics, Faculty of Dentistry, Chulalongkorn ...

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work. As you sit and read, they are faithfully ...