Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead ...

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead increase the risk of chronic liver damage and cancer as we age.

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Hepatic stellate cells (HSCs) are activated to heal the liver when it has a lesion (such as fibrosis or fatty liver); their function is to protect the liver by producing an extracellular matrix ...

Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central finding of a new study led by researchers at the Massachusetts Institute of ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers from the German Cancer Research ...