A new study shows how one of the cell's most important energy-producing machines is built. Researchers at Karolinska ...

SFI's Annual Stanisław Ulam Lecture Series brings a brilliant and distinguished scientist to Santa Fe each year to deliver a series of public talks on cutting-edge topics, in honor of the late ...

From viruses to humans, life makes microproteins that have evaded discovery until now. By Carl Zimmer You could be forgiven for assuming that scientists know how many kinds of proteins exist. After ...

Researchers have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ribosomes as they convert mRNA into proteins. The ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

Building on previous work from the Tansey lab, here Howard et al. characterize transcriptional and translational changes upon WIN site inhibition of WDR5 in MLL-rearranged cancer cells. They first ...

The chromatin-associated protein WD Repeat Domain 5 (WDR5) is a promising target for cancer drug discovery, with most efforts blocking an arginine-binding cavity on the protein called the ‘WIN’ site ...

Researchers at LMU and Stanford University reveal how cells regenerate protein factories at endoplasmic reticulum. The synthesis of proteins in the cell is a key process of life. By this means, the ...