Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

US FDA grants Orphan Drug Designation to Adolore BioTherapeutics’ Kv7-activating rdHSV-CA8 therapy to treat erythromelalgia: Delray Beach, Florida Friday, January 16, 2026, 17:0 ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to hereditary neuronal sodium ion channel mutationsAdolore's Kv7 voltage-gated po ...

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...

Human pain, it turns out, is not just a product of modern stress or injury, but a legacy written deep into our DNA. New ...

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body ...

Salt and sodium differ, and understanding that helps you manage daily intake. Most sodium comes from packaged foods, so ...

This important study identifies PRRT2 as an auxiliary regulator of Nav channel slow inactivation, proposing that PRRT2 facilitates entry into, and delays recovery from, the slow-inactivated state. The ...

Scientists once believed birds relied only on flight, talons and socialization for survival. But this one proves otherwise: it uses chemistry. For most of modern biology, there was a widely accepted ...

Tetrodotoxin (TTX) is best known as the neurotoxin of the puffer fish, though it also appears in a range of other marine species. You might remember it from an episode of The Simpsons involving a ...

Introduction: Following infarction, heart often undergoes pathological remodeling and dysregulation of sodium and calcium homeostasis, predisposing patients to heart failure and arrhythmias. While ...