For decades, dopamine has been celebrated in neuroscience as the quintessential "reward molecule"—a chemical herald of ...

A study mapped genes linked to schizophrenia and uncovered a mechanism that disrupts synaptic plasticity in affected individuals. The researchers showed the role of three proteins in mediating the ...

New research on the hippocampus, a brain area essential for memory, suggests that new rules of synaptic plasticity best explain how brain activity continually reshapes the way memories are recorded in ...

Memory formation and maintenance fundamentally rely on intricate molecular processes that regulate synaptic strength. Central to this phenomenon is synaptic plasticity – the capacity of neural ...

How do we learn something new? How do tasks at a new job, lyrics to the latest hit song, or directions to a friend’s house become encoded in our brains? The broad answer is that our brains undergo ...

This mitochondrial process supports the brain cells essential to learning, memory and social recognition. We know that mitochondria are the powerhouses of the cell, but what role do they play in ...

Calcium alpha-ketoglutarate, a naturally occurring metabolite, can restore key memory-related brain functions that have been disrupted in Alzheimer’s disease.

A mouse runs through a maze it’s explored a dozen times. But inside its brain, the map is never quite the same. New research from the University of Chicago is shedding light on how the mind ...