A sugar on mycobacteria binds to the immune receptor dectin-1 on host macrophages, helping the bacteria survive and driving ...

A novel iPSC-derived lung-on-chip model mimics human alveolar tissue, revealing macrophage-driven tuberculosis responses.

Texas Biomed researchers find that existing treatments control TB and HIV, but the immune system does not revert to normal, ...

The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. In a study published October 20 in the journal Cell, ...

Down-regulation of plasma exosome-derived apolipoproteins APOA1, APOB, and APOC1 indicates DR-TB status and lipid metabolism regulation in pathogenesis. Group case-controlled study assessed 17 drug ...

Disseminated tuberculosis is a type of tuberculosis (TB) where mycobacteria spread via blood to other organs beyond the lungs. It can cause severe multiple-organ damage in the absence of early ...

New observations of the early stages of tuberculosis infection may turn scientists' understanding of the bug's pathogenesis on its head: clumps of immune cells, called granulomas, long thought to ...

It has been uncertain how Mycobacterium tuberculosis deflects the immune response in humans, though evidence has pointed to host immunometabolism - the intrinsic link between metabolism in immune ...

The chip can simulate breathing and lung disease for an individual, holding promise for testing personalized treatments for tuberculosis.