VEXAS syndrome: When inflammation defies treatment and routine tests

VEXAS syndrome is a rare adult-onset inflammatory disease linked to bone-marrow mutations. Doctors explain why it is often ...

Single-Cell Method Maps Pre-Malignant Mutations in Solid Tissues

Researchers developed a single-cell sequencing method that simultaneously measures cancer-linked DNA mutations and gene activity in solid tissues. Applying the approach to human esophageal samples ...
Frontiers

Interplay between Environmental Drivers and Genetic or Epigenetic Predispositions on Gastrointestinal Cancer Evolution

Gastrointestinal (GI) cancers represent a complex interplay of genetic mutations, epigenetic alterations, and environmental factors. The initiation and progression of these cancers are influenced by ...
Frontiers

Population Genomic Screening in Primary Care Leveraging Community Partnerships

Genetic conditions with actionable interventions affect nearly 10% of populations in the United States and internationally - ...
The American Journal of Managed Care

CheckMate 9LA at 6 Years Shows Enduring Benefits From Dual Immunotherapy Plus Chemotherapy in Metastatic NSCLC

CheckMate 9LA showed a 26% overall survival benefit for metastatic NSCLC patients treated with nivolumab and ipilimumab plus ...
News-Medical.Net on MSN

Single-cell technique maps pre-malignant gene mutations in solid tissues

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...
The Citizen

The one health check no man should go without this year

Every new year brings fresh ambitions … moving more, eating better, and finally slowing down. But real self-care isn’t just ...
Science Daily

The fatal mutation that lets cancer outsmart the human immune system

Scientists at UC Davis discovered a small genetic difference that could explain why humans are more prone to certain cancers than our primate cousins. The change affects a protein used by immune cells ...