Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...
DEAH helicases participate in pre‐messenger RNA splicing and ribosome biogenesis. The structure of yeast Prp43p‐ADP reveals the homology of DEAH helicases to DNA helicases and the presence of an ...
This important study elucidates the molecular function of the SARS-CoV-2 helicase NSP13, which inhibits the transcriptional activity of the YAP/TEAD complex in vitro and in vivo. The evidence ...
1 Henan Joint International Research Laboratory of Veterinary Biologics Research and Application, Anyang Institute of Technology, Anyang, China 2 Institute for Animal Health & UK-China Centre of ...
MUNICH, June 16, 2025 /PRNewswire/ -- Innovative Molecules GmbH today announced the completion of enrollment in the Phase 1b portion of its ongoing Phase 1b/2a clinical trial evaluating IM-250, a next ...
WEST LAFAYETTE, Ind. — Purdue University scientists have identified the Supinoxin small-molecule drug as a possible new therapy for small-cell lung cancer (SCLC). “Some cancer types are incredibly ...
Image for representation purpose only. Using cutting-edge cryo-electron microscopy, scientists at the University of Leicester have captured the first detailed “molecular movie” showing DNA being ...
THUWAL, Saudi Arabia — Scientists have finally captured footage of the microscopic machinery that allows our cells to copy DNA—a fundamental process necessary for life itself. Using a sophisticated ...
1 Department of Biochemistry, University of Colorado Boulder, Boulder, CO, United States 2 Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, CO, United States Recent research ...
A new study has identified USP50, a protein that helps regulate enzymes during DNA replication, ensuring proper use of nucleases and helicases. The discovery sheds light on how cells manage ...