Researchers used a modular sequence of copper-catalyzed azide–alkyne cycloaddition (CuAAC), sulfur (VI) fluoride exchange (SuFEx), and Michael addition reactions to quickly assemble ...

3-Hexyne, aka diethylacetylene, is a symmetric alkyne that is used in organic and organometallic synthesis. It first appeared in British patent 279,095 (1926) to Michael George Corson, who heated ...

The proposed platform for triple click chemistry has three functional groups that can be independently targeted for replacement by choosing an appropriate reaction partner. This platform is compatible ...

Introduction: Hydrogels closely resemble natural soft tissue, both mechanically as well as physicochemically, making them ideal biomaterials. Hydrogels made of synthetic polymers pose an advantage ...

Using cycloalkenes, acetylenecarboxylates, and terminal alkynes, researchers at Tokyo Institute of Technology (Tokyo Tech) have successfully produced chiral 3-methylenecyclopent-1-ene derivatives with ...

The 2022 Nobel Prize in Chemistry was awarded to Carolyn Bertozzi, Morten Meldal, and Barry Sharpless for the development of click chemistry and bioorthogonal chemistry. Each laureate played a crucial ...

Alkynes are prized among chemists for their uniquely reactive carbon-carbon triple bonds, which make them excellent coupling partners in click chemistry, for example. Now, chemists at the University ...

Chemists looking to make explosives will often load their molecules with nitrogen atoms, which release energy as they break apart to form N 2 and other small molecules. Researchers have now prepared ...