The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...

The partners are launching ImmuneScape, a multiomics program using spatial and single-cell sequencing to study immune drivers ...

Researchers at Colorado State University have determined how to use artificial intelligence to modify antibodies so they act ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

A new CRISPR-based approach for tuning gene expression up and down allowed identification of how other genes' expression responds to changes of transcription factors.

Peer-reviewed discovery platform and data in PNAS show that single transcription factor modulation reverses aging-associated gene expression and restores healthy cellular and tissue function in models ...