Stopping cancer cells from entering a soft biomechanical state could help the immune system clear dormant cancer metastasis.
A shift in the balance between two lipids – cholesterol and sphingomyelin – makes hybrid epithelial-mesenchymal cancer cells less responsive to certain chemotherapy drugs.
Lipid imbalance triggered by Snail-driven epithelial–mesenchymal transition creates a cholesterol-dependent vulnerability that can be therapeutically targeted to overcome chemoresistance in cancer.
In a new study published in Nature Communications titled, “The reference genome of the human diploid cell line RPE-1,” researchers from University of Rome La Sapienza have produced the first reference ...
Cells bumping against one another use electricity to identify which of their neighbors has the least energy to expel them. The King's College London study in partnership with the Francis Crick ...
When the lungs are attacked by a virus, the damage doesn't stop there. The body's natural defenses cause inflammation while fighting the virus, often leaving lasting problems. The cells that make up ...
1 Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Yangtze University, Jingzhou, China. 2 Respiratory Diseases Research Institution of Yangtze University, ...
MAPK signaling works like a molecular switchboard inside epithelial cells, turning outside stress into gene-level commands. IL-33 is an alarm signal cytokine that normally stays tucked inside airway ...
Chinese scientists have discovered a common mechanism by which structurally distinct proteins elicit an allergic reaction, showing they cause the formation of pores in epithelial airway cells. That ...
In a new paper appearing in the Journal of Investigative Dermatology, a leading scientific publication in the field of research on skin and connective tissue, The Hormel Institute, University of ...
Neurons talk to one another using electricity. If you could hear these impulses, they might sound like constant, rapid-fire chatter all over the nervous system. Heart muscle cells do something similar ...
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