Researchers expand human genome map to 2.37 million regulatory DNA elements

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

First-time use of AI for genetic circuit design demonstrated in a human cell line

There are hundreds of cell types in the human body, each with a specific role spelled out in their DNA. In theory, all it ...
eLife

Chromosomes: Finding a role for non-coding DNA in trypanosomes

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.
Labroots

New Insights Into the Genetics of Blindness

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...
AZoLifeSciences on MSN

Deep learning–based codon optimization framework boosts protein expression in E coli

By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Nature

How viral RNAs escape a host mechanism that controls translation

This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

Can indigenous efforts at genome-edited crop breeding offer food security?

Restricted access to genome-editing technologies poses serious challenges for countries like India that urgently need such ...

Unusual genetic code in Antarctic microbes yields rare amino acid

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...