Insurance data can help fill gaps between longer medical trials for patients up against the clock

Randomized clinical trials remain the gold standard for establishing a medication's effects, producing the evidence by which ...
FierceBiotech

FDA steers cancer CAR-T developers toward randomized superiority trials in policy shift

The FDA is raising the bar for approval of CAR T-cell therapies in oncology. Under plans outlined by the FDA’s biologics chief Vinay Prasad, M.D., the agency will require developers of many CAR-Ts to ...
The Verge

The Luigi Mangione trial is all about narrative control

is features writer with five years of experience covering the companies that shape technology and the people who use their tools. On Monday, several dozen members of the public are lined up outside ...
The New York Times

What Are Clinical Trials, and How Do They Work?

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...
ahajournals.org

Randomized Controlled Trial of Mechanical Thrombectomy With Anticoagulation Versus Anticoagulation Alone for Acute Intermediate-High Risk Pulmonary Embolism: Primary Outcomes ...

Background: Patients with intermediate-high risk pulmonary embolism (PE) have an elevated right-to-left-ventricular (RV/LV) diameter ratio and are at risk of early clinical decompensation and ...
Morningstar

Lilly's oral GLP-1, orforglipron, demonstrated superior glycemic control in two successful Phase 3 trials, reconfirming its potential as a foundational treatment in type 2 diabetes

In ACHIEVE-2, orforglipron lowered A1C by up to 1.7% compared to 0.8% with dapagliflozin, meeting the primary endpoint In ACHIEVE-5, orforglipron lowered A1C by an additional 2.1% when taken with ...
Reuters

Ex-diplomat says Thaci lacked control over KLA in Kosovo war crimes trial

Rubin testifies Thaci lacked authority over KLA commanders Thaci and co-accused deny charges of violence against opponents Kosovo tribunal's biggest case, seen as biased by many Kosovars THE HAGUE, ...
BMJ

Target trial emulation to replicate randomised clinical trials using registry data in multiple sclerosis

14 CHU de Strasbourg, Department of Neurology and Clinical Investigation Center, CIC 1434, INSERM 1434, Strasbourg, France 15 Sorbonne Universités, UPMC Paris 06, Brain and Spine Institute, ICM, ...
Business Wire

Baxdrostat demonstrated statistically significant and clinically meaningful reduction in systolic blood pressure in patients with hard-to-control hypertension in the BaxHTN ...

WILMINGTON, Del.--(BUSINESS WIRE)--Positive full results from the BaxHTN Phase III trial showed baxdrostat demonstrated a statistically significant and clinically meaningful reduction in mean seated ...
STAT

Why Silicon Valley should demand clinical trials for its medical AI

Elemento is the director of the Englander Institute for Precision Medicine at Weill Cornell Medicine. Sternberg is the clinical director of the Englander Institute for Precision Medicine. Khozin is ...