Adolore BioTherapeutics Announces FDA Orphan Drug Designation for its Kv7-activating rdHSV-CA8* Therapy in the Treatment of Erythromelalgia

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to ...
Pharmabiz

US FDA grants Orphan Drug Designation to Adolore BioTherapeutics’ Kv7-activating rdHSV-CA8 therapy to treat erythromelalgia

US FDA grants Orphan Drug Designation to Adolore BioTherapeutics’ Kv7-activating rdHSV-CA8 therapy to treat erythromelalgia: Delray Beach, Florida Friday, January 16, 2026, 17:0 ...
eLife

Functionally coupled ion channels begin co-assembling at the start of their synthesis

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Adolore Biotherapeutics, Inc.: Adolore BioTherapeutics Announces FDA Orphan Drug Designation for its Kv7-activating rdHSV-CA8* Therapy in the Treatment of Erythromelalgia

Orphan Drug Designation applies to approximately 50,000 Patients who predominantly suffer from severe chronic pain due to hereditary neuronal sodium ion channel mutationsAdolore's Kv7 voltage-gated po ...
Yahoo Malaysia

Salt vs. Sodium: What's the Difference? Health Experts Explain

In its natural state, salt is a mineral that can help preserve food and enhance its flavor. "Bacteria cannot thrive in high concentrations of salt," Lena Beal, M.S., RDN. LD, points out. Salt's ...
News Medical

Small shifts in blood sodium may influence human brain excitability

Even within the healthy range, small differences in blood sodium were associated with measurable changes in brain excitability, offering new insight into how subtle physiology may shape neural ...

Encoded Therapeutics Announces U.S. FDA Breakthrough Therapy Designation Granted to ETX101 for the Treatment of Dravet Syndrome

Encoded Therapeutics, Inc. ("Encoded"), a clinical-stage biotechnology company developing precision genetic medicines for severe neurological disorders, today announced that the U.S. Food and Drug ...
Morning Overview on MSN

A breakthrough just revealed the ancient source of human pain

Human pain, it turns out, is not just a product of modern stress or injury, but a legacy written deep into our DNA. New ...

Hidden molecular switch controls taste, metabolism and gut function

Northwestern University scientists have uncovered a hidden molecular "control switch" inside a protein that helps the body ...

Control valve discovered in gut’s plumbing system

Healthy digestion depends on a delicate balance of fluid in the gut. At the heart of that balance are epithelial cells, which line the intestinal wall and control how salt and water move in and out of ...

Control valve discovered in gut's plumbing system may hold answers to constipation and diarrhea

Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how much fluid moves into the gut. These common issues affect millions of people in ...
PharmiWeb

Harmony Biosciences Guides to Over $1 Billion in WAKIX® Revenue in 2026; Advancing Robust Late-Stage Pipeline With Potential for Long-term Value Creation

WAKIX 2025 Preliminary Net Revenue of ~$868 Million; 2026 WAKIX Net Revenue Guidance of $1.0 – $1.04 Billion on Track for Blockbuster Status in NarcolepsyOn Track to Extend the Pitolisant Franchise ...