Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how ...

The human gut replaces its cells faster than any other tissue in the body. Every few days, fresh cells are produced by specialized stem cells that ...

Teeth function not only because of the hard enamel on the surface, but also because they have roots that anchor them firmly ...

The Cambridge, Massachusetts-based company – known as FogPharma until a rebrand in 2024 – needs cash for pivotal trials of ...

What the research is about Teeth function not only because of the hard enamel on the surface, but also because they ...

Scientists have found that combining silybin with carvedilol works far better against liver fibrosis than either drug alone.

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

A research team reports a promising new strategy: combining two already-approved drugs—silybin, a natural liver-protective compound, and carvedilol, a widely used cardiovascular medicine—to powerfully ...

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk and may be reversible.

A common pinworm medication may stop and reverse cancer growth in Merkel cell carcinoma, an aggressive form of skin cancer, according to research led by University of Arizona Cancer Center researchers ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Elevated WNT signalling triggers a wound-like ...

This cover highlights the article Macrophage metabolic reprogramming during dietary stress influences adult body size in Drosophila by Tina Mukherjee, Anusree Mahanta and colleagues. The cover artwork ...