Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. RNA-binding proteins are identified as regulators of cardiac disease; DDX5 (dead-box helicase 5) is a master regulator of ...

Enrique M. De La Cruz, an international leader in molecular motor proteins and the cytoskeleton, was recently appointed the William R. Kenan, Jr. Professor of Molecular Biophysics and Biochemistry, ...

The DEAH/RNA helicase A (RHA) helicase family comprises proteins involved in splicing, ribosome biogenesis and transcription regulation. We report the structure of yeast Prp43p, a DEAH/RHA helicase ...

Viruses have limited genetic material -- and few proteins -- so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now researchers have shown how the ...

Viruses have limited genetic material - and few proteins - so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now, in a study published in the ...

Viruses have limited genetic material—and few proteins—so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins. Now, in a study published in the journal ...

In a recent study published in the PNAS Journal, researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication. They characterized the ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Research findings offer new insights into cell health and disease as failures in replication licensing can result in cell death or cancer. A study revealed that the licensing protein CDT1 also acts as ...

Function (Fn) keys – F1, F2, F3, etc., come in handy for those who are in dire need of shortcuts on their keyboards. Laptops are usually equipped with such keys but desktop keyboards, especially the ...