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libretexts.org
Signaling: Calcium and Calmodulin
This is a description of the calcium signaling protein, Calmodulin, which mediates essential chemical communication between mammalian cells. This page was originally contributed by Makenzie Duncan, …
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𝐈𝐏𝟑-𝐃𝐀𝐆 𝐂𝐚𝐥𝐜𝐢𝐮𝐦 𝐒𝐢𝐠𝐧𝐚𝐥𝐢𝐧𝐠 𝐏𝐚𝐭𝐡𝐰𝐚𝐲 The IP3-DAG calcium signaling pathway is a crucial mechanism in cellular signal transduction. Here's an overview of the process: 1. Signal Reception: - A signal molecule binds to a G-protein coupled receptor (GPCR) on the cell surface. 2. G-Protein Activation: - The GPCR activates a G-protein by exchanging GDP for GTP on its alpha subunit. 3. Phospholipase C Activation: - The activated G-protein activates phospholipase C (PLC). 4. PI
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